Search variants, regions, and genes
Searches cover 83 million HMT-significant xQTLs and fine-mapped 95% credible-set associations identified from more than 25 billion tested brain xQTLs.
ADSP FunGen xQTL Atlas
Quantitative trait loci (QTLs) describe associations between genetic variants and molecular traits. This Atlas uses data from the ROSMAP, MSBB, Knight-ADRC, and MiGA resources to make harmonized xQTL and fine-mapping results accessible across fourteen brain regions and seven cell types (see About and Methods). Molecular traits represented in the Atlas include single-nucleus and bulk gene expression, protein abundance, histone acetylation, DNA methylation, and splicing events.
Select one of the example queries below, or enter your own query and click Search.
Examples
14
Brain regions
7
Cell types
17,000+
Samples
83M+
HMT xQTL associations
Cell / Tissue Contexts
Distribution of xQTL associations across cell and tissue contexts.
Using this resource
Learn more about this resource
Find information about output formats, abbreviations, data sources, interpretation guidance, and other details about the Atlas.
View brain xQTLs on a genome track
Explore xQTL significance at a region of interest. Search by genomic position or gene symbol and select the tracks to display.
Download significant associations
Download TSV files containing significant associations by variant, target gene, or genomic region.
See file formats and metadata for complete format descriptions.