xQTL Data Portal
Harmonized multi-omic
brain xQTLs
Investigate GWAS hits, genes, and genomic regions across integrated brain datasets from ROSMAP, MSBB, Knight-ADRC, and more.
Integrated brain xQTLs from ROSMAP, MSBB, Knight-ADRC, and more
Examples:
- Investigate GWAS hit: rs74504435 or chr7:54881563:A:G
- Study a gene: BIN1
- Explore genomic loci: chr7:195000-200000
14
Brain regions
7
Cell types
6
Omics types
13,000+
Samples
300M+
xQTL associations
Show abbreviations and term definitions
| Term | Description |
|---|---|
| DLPFC | Dorsolateral prefrontal cortex |
| FC_BA_10 | Frontal cortex Brodmann Area 10 |
| FC_BA_22 | Frontal cortex Brodmann Area 22 |
| FC_BA_36 | Frontal cortex Brodmann Area 36 |
| FC_BA_44 | Frontal cortex Brodmann Area 44 |
| PC | Parietal cortex |
| PCC | Posterior cingulate cortex |
| PHG | Parahippocampal gyrus |
| AC | Anterior caudate |
| exc | Excitatory neuron |
| inh | Inhibitory neuron |
| mic | Microglia |
| mic_MFG | Microglia (Medial frontal gyrus) |
| mic_STG | Microglia (Superior temporal gyrus) |
| mic_SVZ | Microglia (Subventricular zone) |
| mic_THA | Microglia (Thalamus) |
| mon | Monocyte |
| oli | Oligodendrocyte |
| opc | Oligodendrocyte progenitor cell |
| ast | Astrocyte |
| Knight-ADRC | Knight Alzheimer's Disease Research Center |
| MSBB | Mount Sinai Brain Bank |
| MiGA | Microglia Genomic Atlas |
| ROSMAP | Religious Orders Study / Memory and Aging Project |
| ROSMAP_snuc_DeJager | ROSMAP single-nucleus (DeJager lab) |
| ROSMAP_snuc_Kellis | ROSMAP single-nucleus (Kellis lab) |
| ROSMAP_snuc_mega | ROSMAP single-nucleus (mega-analysis) |
| eQTL | Expression QTL |
| haQTL | Histone accessibility QTL |
| mQTL | Methylation QTL |
| pQTL | Protein QTL |
| sQTL | Splicing QTL |
| snuc-eQTL | Single-nucleus expression QTL |