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ADSP FunGen-AD xQTL data portal

ADSP FunGen-AD xQTL Portal

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Harmonized multi-omic brain xQTLs

Investigate GWAS hit, gene, or genomic region

Integrated brain xQTLs from ROSMAP, MSBB, Knight-ADRC, and more
Examples:
Investigate GWAS hit: rs74504435 or chr7:54881563:A:G
Study a gene: BIN1
Explore genomic loci: chr7:195000-200000

14 Brain Regions
7 Cell Types
6 Omics Types
13,000+ Samples
300M+ xQTL associations
xQTL data summmary by xQTL type xQTL data summmary by context
Click to show/hide descriptions for terms/abbreviations used in the plots
termdescription
DLPFCDorsolateral prefrontal cortex
FC_BA_10Frontal cortex Brodmann Area 10
FC_BA_22Frontal cortex Brodmann Area 22
FC_BA_36Frontal cortex Brodmann Area 36
FC_BA_44Frontal cortex Brodmann Area 44
PCParietal cortex
PCCPosterior cingulate cortex
PHGParahippocampal gyrus
ACAnterior caudate
excExcitatory neuron
inhInhibitory neuron
micMicroglia
mic_MFGMicroglia (Medial frontal gyrus)
mic_STGMicroglia (Superior temporal gyrus)
mic_SVZMicroglia (Subventricular zone)
mic_THAMicroglia (Thalamus)
monMonocyte
oliOligodendrocyte
opcOligodendrocyte progenitor cell
astAstrocyte
Knight-ADRCKnight Alzheimer's Disease Research Center
MSBBMount Sinai Brain Bank (MSBB)
MiGAMicroglia Genomic Atlas
ROSMAPReligious Orders Study/Memory and Aging Project (ROSMAP)
ROSMAP_snuc_DeJagerReligious Orders Study/Memory and Aging Project (ROSMAP)
ROSMAP_snuc_KellisReligious Orders Study/Memory and Aging Project (ROSMAP)
ROSMAP_snuc_megaReligious Orders Study/Memory and Aging Project (ROSMAP)
eQTLexpression QTL
haQTLhistone accessibility QTL
mQTLmethylation QTL
pQTLprotein QTL
sQTLsplicing QTL
snuc-eQTLsingle-nucleus expression QTL